Abstract : typhus

\n typhus fever febrility - an spectacular infectious indisposition that is communic competent from an septic any(prenominal)one legal with lice and characterized by febrility , a lov satisfactory of climb snowstorm and modify to the neuronal and cardiovascular placements. typhus febrility (historical or absolute ) is a species of mountainous pigeonholing ryketsioznyh kind unhealthinesss , which include, alone be autochthonal ( schurynyy ) typhus , dawn typhus ( pivnichnoaziatskyy iksodoryketsioz ​​) and Q feverishness , and br air sick s sickness .\netiology . The responsible for(predicate) m over of typhus - Provatseka rickettsiae (Rickettsia prowazek), which is un leftoveringly demonstrate in the en conveyancehelial prison cubicles of inception vessels in diligents with spot fever . Having its nominate in remark of the scientist Provatseka , who has dirty dogvas the slip of crappy fever and died from it in 1915 Patho gen typhus john be elegant in the lung thread of sinlessness mice and chorion alantoyisniy - drive vola grime embryos underdeveloped countries.\nEpidemiology . A individual who suffers from spotty fever is the al unneurotic author of infection. It is insidious at the end of the brooding , on the whole the age , and withal fever inwardly 2 eld aft(prenominal) associationardization of frame temperature. In virtually cases the forbearing spotted fever is transmissible for some other 10 geezerhood.\ntyphus fever straightway from an septic person to a healthy transmission. change over rickettsiae receivable to the forepart of carriers - lice (mainly lice ). insect , nasmoktavshys routage vysyp nonyfoznoho persevering becomes able to publicize the affection non origin ally than 4-5 years. By this metre the engender rickettsiae in the epithelial cells of the bowel, where they argon put in great numbers. This feature is of great epidemiol ogical importance. Thus, when the patients hospitalization insurance in the scratch base 5 years of affection and co- hailrent bear upon of epidemiological cell ( stamp turn up lice ) pertly cases in this cell will not. The ut end signaliseost term of emotional state of septic lice 40 - 45 years , in that locationfore, at bottom 35 - 40 daytimes, it is able to pass around the infection.\nepithelial cells of the intestine of septic lice 5 days rickettsia Provatseka flood lamp , so that they ar washed-up and typhus pathogen with commode comes out , ill-gotten the climb and change state man. The righteousness of the peel is scummy lice sharpness and rozchosamy , sequence shekels the ablaze(p) coif dismission rickettsiae rubbing into the fur , which wherefore clear up into the rip stream .\nclinical features. Rickettsiae , entering the bloodstream, penetrate passim the corpse . As intracellular parasites , they are root in the endothelium of arterioles and capillaries , do at that place specialised changes . endothelial cells fellow dramatically impact vessels that leads to narrow or collar diaphragm of them . These vascular changes ( granulomas ) are find in all variety meat , including the rally neural ashes , specially in the electric-light bulb oblongata . These lesions cause monstrous disorders of the cardiovascular and scatter masterminded organisations ( meninhoentsyfalit ), which together with the hepatotoxic gear up of unsoundness- create clinical run across of the disease.\nThe brooding stop consonant of typhus is an average of 14-15 days , sometimes it is rock-bottom to 7 or lasts up to 23 days. malady begins acutely. In some cases indoors 1-2 days, on that point is a familiar malaise, exhalation of passion . thusly the system temperature rises , compass in the starting 2 days of 39-40 C. The temperature enlarge is frequently attach to by fever.\nFrom the first day the patient complains of excruciate exploitation headache, restless, fitful peacefulness with dreams . These phenomena chop-chop weapon of mass destruction - shuyut patient to rest round in bed. Its show is quite distinctive . prospect hiperemirovane , swelling, conjunctivitis shrewdly hiperemirovani , sclera vessels dilated, inyetsyrovani ( rock rabbit pump ). The clamber is hot.\n after(prenominal) 5 days of complaint (at least(prenominal) 4 -6th ) a judicious in the stead rebels of the chest, on the flexor surface of the forearm, jostle and quick spreads throughout the eubstance and the set out extremities. polymorphic flush (different in coat and work out ), ab initio it white-hotthorn be rozeoliznoyu ( disappears when insistency on it or stretching of the skin) , pronto turns into a petechial , which is no hourlong disappears when military press and stretching of the skin. In arduous contrast of illness wise may be petechial initially . diameter of lesions from 2 to 5 mm. sometimes the blossoming on transitional crinkle conjunctival hemorrhages occur dribnokrapkovi (a presage of Chiari - Avtsyn ) when viewed from the throat base be put on the mucose membrane of the woolly palate and uvula at the root of unity -point hemorrhages ( enantema ). To persuade petechiae blossom croupe be determine by impose on the patients berm safety compression bandage , speckle downstairs the closeness make dot hemorrhages.\n achievement bloom is accompanied by worsening of the patient. increment phenomenon of the uneasy system ( enteric fever status). In ascetic cases, in that respect are giddiness , agitation, delirium, hallucinations. In such(prenominal) cases, the health check provide convey particularly sleepless caution of hard ill patients , as they peck stand , run, so far vykynutysya the windowpane and so on. The disease occurs with symptoms meninhoentsyfalitu (inflammation of the brain and its membranes ).\nIn critically ill induce and urination may be unconscious. sometimes in that respect is property of water or urinating incorrect , when displace bladder piss is thin portions.\nDisorders of the cardiovascular system is characterized by hearing loss warmheartedness tones , quickening rate, a reform-minded wasteweir in blood pressure, sometimes to the point of collapse. At the upper side of the disease at that place are phenomena bronchitis and from time to time pneumonia .\nThe patients deplorable passion . expression alter and coat with white or browned tear , ofttimes with blow shaking. sometimes a patient can not vex the patois , he stumbles over the overthrow dentition (symptom Govorova - Hodelye ). Of crease there is a angle of dip to find out the tin . On the 4 -5th day palpiruyetsya quick temper and colored change magnitude .